• 19. Fiat Lux Freshman Seminars

    Units: 1

    Seminar, one hour. Discussion of and critical thinking about topics of current intellectual importance, taught by faculty members in their areas of expertise and illuminating many paths of discovery at UCLA. P/NP grading.

  • 99. Student Research Program

    Units: 1 to 2

    Tutorial (supervised research or other scholarly work), three hours per week per unit. Entry-level research for lower division students under guidance of faculty mentor. Students must be in good academic standing and enrolled in minimum of 12 units (excluding this course). Individual contract required; consult Undergraduate Research Center. May be repeated. P/NP grading.

  • 110. Introduction to Cytogenetics

    Units: 4

    Lecture, one hour; discussion, two hours. Limited to upper division biology students. Cytogenetics is branch of genetics concerned with study of structure and function of cells, especially chromosomes. Coverage of broad range of topics on both clinical aspects and research in cytogenetics. Studies provide important paradigms to understand structure of chromosomes, mechanisms of chromosome segregation, diseases, and problems created for numerical and structural abnormalities of human chromosomes as well as study of new techniques in molecular cytogenetics, including fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH), and array CGH to diagnose constitutional syndromes and cancer. Journal club sessions include discussion of two journal articles per meeting (one clinical and one basic/translational). Presentation of at least one journal article and leading of one group discussion required. Letter grading.

  • 188SA. Individual Studies for USIE Facilitators

    Units: 1

    Tutorial, to be arranged. Enforced corequisite: Honors Collegium 101E. Limited to junior/senior USIE facilitators. Individual study in regularly scheduled meetings with faculty mentor to discuss selected USIE seminar topic, conduct preparatory research, and begin preparation of syllabus. Individual contract with faculty mentor required. May not be repeated. Letter grading.

  • 188SB. Individual Studies for USIE Facilitators

    Units: 1

    Tutorial, to be arranged. Enforced requisite: course 188SA. Enforced corequisite: Honors Collegium 101E. Limited to junior/senior USIE facilitators. Individual study in regularly scheduled meetings with faculty mentor to finalize course syllabus. Individual contract with faculty mentor required. May not be repeated. Letter grading.

  • 188SC. Individual Studies for USIE Facilitators

    Units: 2

    Tutorial, to be arranged. Enforced requisite: course 188SB. Limited to junior/senior USIE facilitators. Individual study in regularly scheduled meetings with faculty mentor while facilitating USIE 88S course. Individual contract with faculty mentor required. May not be repeated. Letter grading.

  • 199. Directed Research in Pathology

    Units: 2 to 4

    Tutorial, 10 hours. Limited to juniors/seniors. Supervised individual research or investigation under guidance of faculty mentor. Culminating paper or project required. May be repeated for credit. Individual contract required. P/NP or letter grading.

  • 207. Gross and Developmental Anatomy for Graduate Students

    Units: 12

    Lecture/laboratory, three four-hour sessions (16-week semester). Gross anatomy, embryology, and radiological anatomy of human body as taught by lectures, demonstrations, and dissections. Trunk and extremities; head and neck. Letter grading.

  • M215. Interdepartmental Course: Tropical Medicine

    Units: 2

    (Same as Medicine M215 and Pediatrics M215.) Lecture, two and one half hours. Preparation: basic courses in microbiology and parasitology of infectious diseases in School of Medicine or Public Health. Study of current knowledge about diseases prevalent in tropical areas of world. Major emphasis on infectious diseases, with coverage of problems in nutrition and exotic noninfectious diseases. Syllabus supplements topics covered in classroom. S/U grading.

  • 222. Hematopoiesis: Basic Biology and Clinical Implications

    Units: 4

    Lecture, three hours; discussion, one hour. Senior undergraduate students considered on case by case basis. In-depth study of concepts and paradigms in hematopoietic development. Mammalian hematopoiesis and normal development, with focus on molecular regulation of cellular development and equal emphasis on conceptual and experimental aspects of knowledge in field. Discussion of important pathological states within hematopoietic system, as well as established and novel avenues for therapy. Topics include hematopoietic stem cells and niche, transcriptional and epigenetic regulation of hematopoiesis, B- and T-lymphocyte development, myeloid, erythroid, and platelet development, immune responses, myeloid and lymphoid neoplasia, and bone marrow transplantation/gene therapy. S/U or letter grading.

  • M229. Molecular Mechanisms of Host/Pathogen Interaction

    Units: 4

    (Same as Microbiology M229.) Lecture, two hours; discussion, two hours. Enforced requisites: Molecular Biology 254A through 254D. Molecular mechanisms of microbial interactions with eukaryotic host cells that result in disease or pathogen survival. Topics include pathogenesis of common viruses, bacteria, fungi, and parasites, basis of toxin-mediated cellular damage, and immune suppression of microbial tissue damage. Letter grading.

  • M237. Cellular and Molecular Basis of Disease

    Units: 4

    (Same as Biological Chemistry M237.) Lecture, two hours; laboratory, two hours. Preparation: one course each in molecular biology, cell biology, and biological chemistry. Discussion of key issues in disease mechanisms, with emphasis on experiments leading to understanding of these mechanisms. Identification of important questions still remaining unanswered. Letter grading.

  • 238. Histology and Pathology for Graduate Students

    Units: 2

    Laboratory, two hours. Designed for UCLA ACCESS or Cellular and Molecular Pathology Ph.D. students. Basic introductory knowledge of normal tissue, pathologic processes, and animal models as observed by light microscopy. Letter grading.

  • 240. Transplantation Immunology from Benchside to Bedside

    Units: 4

    Lecture, three hours; laboratory, one hour. Preparation: knowledge of basic immunology. Limited to graduate students. New developments in organ transplantation, updates on basic science of immune mechanisms, integration of basic science principles with clinical practice. Letter grading.

  • M255. Mapping and Mining Human Genome

    Units: 3

    (Same as Human Genetics M255.) Lecture, three hours. Basic molecular genetic and cytogenetic techniques of gene mapping. Selected regions of human genomic map scrutinized in detail, particularly gene families and clusters of genes that have remained linked from mouse to human. Discussion of localizations of disease genes. S/U or letter grading.

  • 256. Seminar: Viral Oncology

    Units: 2

    Seminar, two hours. Advanced research seminar designed to consider current developments in field. Selection of current subjects and publications dealing with tumor viruses, oncogenesis, development, and cellular regulation. S/U or letter grading.

  • M257. Introduction to Toxicology

    Units: 4

    (Same as Pharmacology M257.) Requisite: Pharmacology M241. Biochemical and systemic toxicology, basic mechanisms of toxicology, and interaction of toxic agents with specific organ systems.

  • M258. Pathologic Changes in Toxicology

    Units: 4

    (Same as Pharmacology M258.) Designed to give students experience in learning normal histology of tissues which are major targets of toxin and the range of pathologic changes that occur in these tissues (liver, bladder, lung, kidney, nervous system, and vascular system).

  • 260. Immunopathology

    Units: 4

    Lecture, two hours; discussion, one hour; laboratory, one hour. Requisite: Microbiology 261. Advanced information for graduate and advanced undergraduate students regarding immune system anatomy, lymphocytic development, acute and chronic inflammation, hypersensitivity, and autoimmunity. Letter grading.

  • 262. Cytogenetics and Genomics

    Units: 3

    Lecture, three hours. Comprehensive guide so students gain sufficient knowledge in conventional and state-of-art cytogenetic and genomic principles and techniques and their utility in clinical and research applications. Focus on relationship between various chromosomal and genomic abnormalities in humans as identified by basic and advanced technologies such as fluorescence in situ hybridization (FISH), chromosomal microarray analysis (CMA), and next-generation sequencing (NGS). All aspects of molecular cytogenetics and cytogenomics through didactic teaching sessions, journal clubs, and interactive discussions. S/U or letter grading.

  • 270. Basic and Clinical Aspects of Developmental Hematology

    Units: 4

    Lecture, two hours. Graduate- and postgraduate-level course that covers broad range of topics in both basic and clinical aspects of developmental hematology. Pediatric hematologic disorders provide important paradigm to study other developmental systems. Subjects include hematopoiesis, basic stem cell biology, angiogenesis, alternative models to study developmental hematology (zebrafish and "Drosophila"), basic physiology of normal and abnormal red cells, platelets, and white cells, leukemogenesis and novel therapeutics to treat leukemia, basic and clinical stem cell transplantation, state-of-the-art methods in developmental hematology (genomics, proteomics, and gene therapy, design of clinical trials, and biomathematical modeling and statistics in developmental hematology. Letter grading.

  • M272. Stem Cell Biology and Regenerative Medicine

    Units: 4

    (Same as Molecular, Cell, and Developmental Biology M272.) Lecture, two hours; discussion, two hours. Designed for graduate students. Presentation of current knowledge of embryonic and adult stem cells and factors that regulate their growth and development. Major emphasis on how advances in cell and molecular biology and tissue engineering can be applied to use of stem cells in regenerative medicine. Bioethical and legal issues related to stem cell research. S/U or letter grading.

  • 280. Clinical Aspects and Molecular Biology of Bone Marrow Failure

    Units: 4

    Lecture, two hours. Limited to graduate students. Coverage of broad range of topics on both clinical aspects and molecular pathogenesis of bone marrow failure syndromes. Studies provide important paradigms to understand fundamental mechanisms of human disease in addition to normal and abnormal blood cell development. Topics include basic biology and clinical features of aplastic anemia, myelodysplastic syndromes, Diamond Blackfan Anemia, Schwachman Diamond Syndrome, Fanconi Anemia, Dyskeratosis Congenita, Paroxysmal Nocturia Hemoglobinuria, flow cytometry, and research approaches to study bone marrow failure syndromes. Journal club sessions include discussion of two journal articles per meeting -- one clinical and one basic/translational. Students present at least one journal article and lead group discussion. S/U or letter grading.

  • 294. Basic Concepts in Oncology

    Units: 4

    Lecture, three hours. Fundamental biological, genetic, and molecular process involved in genesis and growth of cancer cells and diagnosis, characterization, and treatment of cancer. Letter grading.

  • 296. Research Topics in Pathology

    Units: 1 to 2

    Research group meeting, one to two hours. Limited to departmental graduate students. Advanced study and analysis of current topics in pathology. Discussion of current research and literature in research specialty of faculty member teaching course. May be repeated for credit. S/U grading.

  • 298A. Current Research in Disease Mechanisms

    Units: 2

    Lecture, 90 minutes. Preparation: one course each in molecular biology, cell biology, and biological chemistry. Designed for graduate experimental pathology students. Current research in disease mechanisms, with strong emphasis on experimental approach in pathology. Topics include genetic and metabolic disorders, thyroid disease, immunology, atherosclerosis, infectious diseases, and Alzheimer's disease. S/U or letter grading.

  • 298B. Current Research in Disease Mechanisms

    Units: 2

    Lecture, 90 minutes. Preparation: one course each in molecular biology, cell biology, and biological chemistry. Designed for graduate experimental pathology students. Current research in disease mechanisms, with strong emphasis on experimental approach in pathology. Topics include genetic and metabolic disorders, thyroid disease, immunology, atherosclerosis, infectious diseases, and Alzheimer's disease. S/U or letter grading.

  • 298C. Current Research in Disease Mechanisms

    Units: 2

    Lecture, 90 minutes. Preparation: one course each in molecular biology, cell biology, and biological chemistry. Designed for graduate experimental pathology students. Current research in disease mechanisms, with strong emphasis on experimental approach in pathology. Topics include genetic and metabolic disorders, thyroid disease, immunology, atherosclerosis, infectious diseases, and Alzheimer's disease. S/U or letter grading.

  • 298D. Current Research in Disease Mechanisms

    Units: 2

    Lecture, 90 minutes. Preparation: one course each in molecular biology, cell biology, and biological chemistry. Designed for graduate experimental pathology students. Current research in disease mechanisms, with strong emphasis on experimental approach in pathology. Topics include genetic and metabolic disorders, thyroid disease, immunology, atherosclerosis, infectious diseases, and Alzheimer's disease. S/U or letter grading.

  • 375. Teaching Appentice Practicum

    Units: 1 to 4

    Seminar, to be arranged. Preparation: apprentice personnel employment as teaching assistant, associate, or fellow. Teaching apprenticeship under active guidance and supervision of regular faculty member responsible for curriculum and instruction at UCLA. May be repeated for credit. S/U grading.

  • 596. Directed Individual Study or Research

    Units: 4 to 12

    Tutorial, to be arranged. Individual research with members of the staff or of other departments, the latter for purpose of supplementing programs available in department. S/U grading.

  • 597. Preparation for Qualifying Examinations

    Units: 2 to 8

    Tutorial, to be arranged. Preparation: one year of pathology coursework. Individual study for qualifying examinations. S/U grading.

  • 599. Preparation of Ph.D. Dissertation

    Units: 2 to 12

    Tutorial, to be arranged. Preparation: completion of qualifying examinations and majority of Ph.D. research. Writing and completion of dissertation. S/U grading.