C147. Applied Tissue Engineering: Clinical and Industrial Perspective
Lecture, three hours; discussion, two hours; outside study, seven hours. Requisites: course CM102, Chemistry 20A, 20B, 20L, Life Sciences 1 or 2. Overview of central topics of tissue engineering, with focus on how to build artificial tissues into regulated clinically viable products. Topics include biomaterials selection, cell source, delivery methods, FDA approval processes, and physical/chemical and biological testing. Case studies include skin and artificial skin, bone and cartilage, blood vessels, neurotissue engineering, and liver, kidney, and other organs. Clinical and industrial perspectives of tissue engineering products. Manufacturing constraints, clinical limitations, and regulatory challenges in design and development of tissue-engineering devices. Concurrently scheduled with course C247. Letter grading.